News
Last updated:  

Gene That May Let You Eat What You Wish Without Fear of Gaining Weight

While this may sound like the epitome of news that is too good to be true, a new discovery in the medical field may soon allow you to eat without fear of gaining weight. Yes, you may be able to eat as much food as you want in the near future and not worry about offsetting it with exercise or diet pills. The key to this breakthrough is a newly discovered gene that naturally is found in the human body.

When the gene known as RCAN1 was tested in the lab it offered promising results to the study team. Scientists removed this gene in mice, the mice were then exclusively fed a high fat diet. Even after eating this high fat diet for months, the mice did not seem to gain any additional weight.

The team of international researchers who were behind the study say these findings offer hope that a similar approach for gene manipulation can prove to be just as effective with humans. If this is the case, it could open doors to new ways of combating obesity and serious diseases such as hart disease, diabetes, and obesity.

Led by Professor Damien Keating at Flinders University, this research study was focused on unlocking the power of genes and finding new ways to help people live healthier lives and battle the growing epidemic of obesity that is raging in this country. “We know a lot of people struggle to lose weight or even control their weight for a number of different reasons. The findings in this study could lead to the development of a pill which would target the function of RCAN1 and may result in weight loss,” Professor Keating says.

Obesity is of a major concern when it comes to health and wellness as it results in an augmented risk of serious diseases. Gene manipulations can prove to be life changing and can help people live healthier lives. While things are still in the early stages of research, drug development has already been started and additional studies are being done to help streamline the process and improve results of the gene manipulations.

Professor Keating is hopeful that continued research and study will improve results and soon open up new applications and uses for this revolutionary breakthrough. “In light of our results, the drugs we are developing to target RCAN1 would burn more calories while people are resting. It means the body would store less fat without the need for a person to reduce food consumption or exercise more…We looked at a variety of different diets with various timespans from eight weeks up to six months, and in every case, we saw health improvements in the absence of the RCAN1 gene”.

The researchers say these findings open up a potentially simple treatment but further studies are required to determine if they translate the same results to humans. With increased funding and assistance from the Australian government through the National Health and Medical Research Council, the goal is to continue the exploration of more viable options and applications. These results demonstrate the opportunity to make a real difference in the ongoing battle against the obesity epidemic. Time and additional research are needed and we will see more results in the near future.

Citations
David Rotter, Heshan Peiris, D Bennett Grinsfelder, Alyce M Martin, Jana Burchfield, Valentina Parra, Christi Hull, Cyndi R Morales, Claire F Jessup, Dusan Matusica, Brian W Parks, Aldons J Lusis, Ngoc Uyen Nhi Nguyen, Misook Oh, Israel Iyoke, Tanvi Jakkampudi, D Randy McMillan, Hesham A Sadek, Matthew J Watt, Rana K Gupta, Melanie A Pritchard, Damien J Keating, Beverly A Rothermel. Regulator of Calcineurin 1 helps coordinate whole‐body metabolism and thermogenesis. http://embor.embopress.org/content/19/12/e44706

Adnan Munye

A certified personal trainer, Adnan specialises in weight loss, muscle building, body conditioning, core strengthening and injury rehabilitation. Adnan comes from a sporting background, where he has played football, badminton, rugby, and swimming all at various levels.

Adnan has always been passionate about health and fitness. He comes from a sporting background playing football, badminton, rugby, and swimming at various levels from a young age.